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pentobarbital will reduce the extent or result of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will decrease the level or outcome of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with strong CYP3A4 inducers will not be recommen